MOTS-c.
A mitochondrial-derived peptide for metabolic efficiency, endurance, and cellular energy.
Pricing is shown after your free assessment, before you commit.
Free to start. No card required.
Reviewed by Lumora clinical team (Licensed provider network)Mixed evidenceSource: Client-approved product catalog; provider review required
Evidence, regulatory status, and fit vary by medication, formulation, route, and individual history.
Is this for you?
This is for you if
- Patients with chronic fatigue or low stamina
- Patients who feel 'tired but wired'
- Patients wanting better workout performance
- Patients pursuing metabolic and longevity support
This isn't for you if
Generally well tolerated. Disclose diabetes or insulin therapy before starting.
MOTS-c
MOTS-c is a peptide encoded within mitochondrial DNA. It acts as a key metabolic regulator — improving how the body uses carbohydrates and fats for energy, supporting endurance, and helping maintain insulin sensitivity. It is sometimes described as an 'exercise mimetic.'
Mechanism and fit.
MOTS-c acts inside the mitochondria — the energy factories of your cells — to improve glucose and fat utilization, support metabolic flexibility, and increase ATP production efficiency. The result is steadier energy, better workout performance, and a more resilient metabolism.
Who this is typically for.
- Patients with chronic fatigue or low stamina
- Patients who feel 'tired but wired'
- Patients wanting better workout performance
- Patients pursuing metabolic and longevity support
What patients
most often ask.
How is MOTS-c different from SLU-PP-332?
Both support metabolic adaptation, but MOTS-c is a mitochondrial-derived peptide that improves cellular fuel usage. SLU-PP-332 activates ERR pathways to mimic exercise adaptations. They target different layers and are sometimes used together.
Who this is typically for.
These are common fit patterns from the approved catalog. Your provider determines whether treatment is appropriate.
- <ul><li>Patients with chronic fatigue or low stamina</li><li>Patients who feel 'tired but wired'</li><li>Patients wanting better workout performance</li><li>Patients pursuing metabolic and longevity support</li></ul>
How this option
is evaluated.
The plan is provider-determined after reviewing your assessment and safety factors.
- Dosing2–3 times weekly.
- Typical duration4–6 week cycles.
- Safety and eligibilityYour provider reviews contraindications, medication interactions, goals, and safety factors before prescribing.
- A licensed provider reviews your assessment before any treatment is recommended.
- You see full pricing - visit fees, medication, labs, follow-up - before you commit.
- Your plan can be adjusted, paused, or stopped based on response and safety. Your clinician is reachable - not a chatbot.
- Compounded medications are not FDA-approved and are dispensed only when prescribed by a licensed provider.
Start with
provider review.
If you are considering MOTS-c, the first step is a free assessment. A provider determines whether it fits your goals and medical history.
A provider determines whether treatment is clinically appropriate.