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Semaglutide + B12.

Compounded semaglutide combined with B12 to support energy during weight management.

1 / 2 / 4 / 6 / 10 mg semaglutide with 0.5 mg B12 per mL · subcutaneous injectable

Pricing is shown after your free assessment, before you commit.

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Is this for you?

This is for you if

  • Patients starting or continuing semaglutide therapy who experience fatigue
  • Patients with low or borderline B12 levels
  • Patients who prefer fewer injections during their weight-management protocol

This isn't for you if

All safety information for semaglutide applies — see the Semaglutide product page. B12 is generally well tolerated. Patients with cobalt or cobalamin sensitivity or Leber's hereditary optic neuropathy should consult their provider.

What it is

Semaglutide + B12

This formulation combines compounded semaglutide — the same GLP-1 receptor agonist used as a standalone — with vitamin B12 in a single weekly injection. B12 is added to support energy metabolism and to address suboptimal B12 status, which can worsen the fatigue some patients experience during GLP-1 titration.

How it works

Mechanism and fit.

The semaglutide component works exactly as it does standalone: regulating appetite, slowing gastric emptying, and improving glucose handling. The B12 component supports energy metabolism, red blood cell formation, and nervous-system health. Combining them in one injection reduces total injections and addresses two needs in a single weekly dose.

When it may fit

Who this is typically for.

  • Patients starting or continuing semaglutide therapy who experience fatigue
  • Patients with low or borderline B12 levels
  • Patients who prefer fewer injections during their weight-management protocol
Semaglutide + B12 - common questions

What patients
most often ask.

Will I get more weight loss with the B12 version?+

The B12 doesn't change the weight-loss effect of semaglutide itself. It's added to support energy and reduce one of the common reasons patients struggle during titration.

When it may fit

Who this is typically for.

These are common fit patterns from the approved catalog. Your provider determines whether treatment is appropriate.

  • <ul><li>Patients starting or continuing semaglutide therapy who experience fatigue</li><li>Patients with low or borderline B12 levels</li><li>Patients who prefer fewer injections during their weight-management protocol</li></ul>
Provider plan

How this option
is evaluated.

The plan is provider-determined after reviewing your assessment and safety factors.

  • DosingWeekly subcutaneous injection, titrated by your provider through the five concentration tiers.
  • Typical durationLong-term, individualized based on response and labs.
  • Safety and eligibilityYour provider reviews contraindications, medication interactions, goals, and safety factors before prescribing.
How care works
  • A licensed provider reviews your assessment before any treatment is recommended.
  • You see full pricing - visit fees, medication, labs, follow-up - before you commit.
  • Your plan can be adjusted, paused, or stopped based on response and safety. Your clinician is reachable - not a chatbot.
  • Compounded medications are not FDA-approved and are dispensed only when prescribed by a licensed provider.

Start with
provider review.

If you are considering Semaglutide + B12, the first step is a free assessment. A provider determines whether it fits your goals and medical history.

Start provider review →

A provider determines whether treatment is clinically appropriate.

Important information
Lumora may prescribe FDA-approved or compounded medications when clinically appropriate. Compounded medications are not approved by the FDA and are dispensed by a licensed pharmacy under the supervision of a licensed provider.